Nigeria Premier Football League 2009/2010 was the 39th season of the competition since its inception. Enyimba FC Was the Champion. Starting on 20 September 2009, it ran to July 7 due to breaks for both the 2010 Africa Cup of Nations and the 2010 FIFA World Cup and a total of 378 of a possible 380 games played. It ran without a sponsor since January due to the pulling out of sponsor Globalcom.
| Champions | Enyimba F.C. |
|---|---|
| Relegated | Wikki Tourists Bayelsa United Gateway F.C. Ranchers Bees |
| 2011 CAF Champions League | Enyimba Kano Pillars |
| 2011 CAF Confederation Cup | Sunshine Stars Kaduna United (cup winner) |
| Matches played | 378 |
| Goals scored | 750 (1.98 per match) |
| Top goalscorer | Ahmed Musa, K. Pillars (18) |
| Biggest home win | Kwara United F.C. 6 Ranchers Bees 0 (June 13) |
| Biggest away win | Shooting Stars 2 Ranchers Bees 0 (June 27)-Played in Minna per League Punishment |
| Highest scoring | 7-Wikki Tourists 3 Kwara United 4 (Oct. 17), |
NPFL 2009/2010 Table
| Pos | Club | P | W | D | L | F | A | GD | Pts |
|---|---|---|---|---|---|---|---|---|---|
| 1 |  Enyimba | 38 | 20 | 10 | 8 | 43 | 25 | 18 | 70 |
| 2 |  Pillars | 38 | 19 | 9 | 10 | 48 | 29 | 19 | 66 |
| 3 |  Sunshine | 38 | 19 | 7 | 12 | 39 | 30 | 9 | 64 |
| 4 |  Kwara | 38 | 18 | 6 | 14 | 43 | 34 | 9 | 60 |
| 5 |  Rangers | 38 | 15 | 13 | 10 | 34 | 22 | 12 | 58 |
| 6 | Warri Wolves | 38 | 17 | 7 | 14 | 50 | 43 | 7 | 58 |
| 7 |  Tornadoes | 38 | 16 | 7 | 15 | 42 | 38 | 4 | 55 |
| 8 |  Heartland | 38 | 16 | 6 | 16 | 37 | 33 | 4 | 54 |
| 9 |  Gombe | 38 | 16 | 4 | 18 | 34 | 33 | 1 | 52 |
| 10 | Kaduna United | 38 | 15 | 7 | 16 | 40 | 45 | -5 | 52 |
| 11 |  3SC | 38 | 14 | 10 | 14 | 27 | 33 | -6 | 52 |
| 12 | Dolphin | 38 | 13 | 12 | 13 | 39 | 39 | 0 | 51 |
| 13 |  Lobi | 38 | 14 | 9 | 15 | 34 | 37 | -3 | 51 |
| 14 | Ocean Boys | 38 | 14 | 8 | 16 | 32 | 36 | -4 | 50 |
| 15 | Zamfara United | 38 | 13 | 10 | 15 | 30 | 46 | -16 | 49 |
| 16 | Sharks | 38 | 14 | 6 | 18 | 45 | 41 | 4 | 48 |
| 17 |  Wikki | 38 | 13 | 8 | 17 | 40 | 38 | 2 | 47 |
| 18 |  Bayelsa | 38 | 13 | 8 | 17 | 40 | 46 | -6 | 47 |
| 19 | Gateway United | 38 | 11 | 7 | 20 | 33 | 46 | -13 | 40 |
| 20 | Ranchers Bees | 38 | 10 | 6 | 22 | 23 | 59 | -36 | 36 |
Champion
CAF Champions League
CAF Confederations Cup
Relegation
